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PPX One Step Propoxyphene Test
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【SUMMARY】

Propoxyphene (PPX) is a narcotic analgesic compound bearing structural similarity to methadone. As an analgesic, Propoxyphene can be from 50-75% as potent as oral codeine. Darvocet™, one of the most common brand names for the drug, contains 50-100 mg of Propoxyphene napsylate and 325-650 mg of acetaminophen. Peak plasma concentrations of Propoxyphene are achieved from 1 to 2 hours post dose. In the case of overdose, Propoxyphene blood concentrations can reach significantly higher levels. In humans, Propoxyphene is metabolized by N-demethylation to yield Norpropoxyphene. Norpropoxyphene has a longer half-life (30 to 36 hours) than parent Propoxyphene (6 to 12 hours). The accumulation of Norpropoxyphene seen with repeated doses may be largely responsible for resultant toxicity.

 

【DIRECTIONS FOR CASSETTE USE】
Allow the test, urine specimen, and/or controls to reach room temperature (15-30°C) prior to testing.
1. Bring the pouch to room temperature before opening it. Remove the test cassette from the sealed pouch and use it within one hour. 
2. Place the test cassette on a clean and level surface. Hold the dropper vertically and transfer 3 full drops of urine (approx. 120μL) to the specimen well (S) of the test cassette, and then start the timer. Avoid trapping air bubbles in the specimen well (S). See the illustration below.
3. Wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10minutes. 


【DIRECTIONS FOR PANEL USE】
Allow the test, urine specimen, and/or controls to reach room temperature (15-30°C) prior to testing.
1. Bring the pouch to room temperature before opening it. Remove the test panel from the sealed pouch and use it within one hour. 
2. Remove the cap. 
3. With the arrow pointing toward the urine specimen, immerse the test panel vertically in the urine specimen for at least 10 to 15 seconds. Immerse the strip to at least the level of the wavy lines, but not above the arrow on the test panel.
4. Replace the cap and place the test panel on a non-absorbent flat surface.
5. Start the timer and wait for the colored line(s) to appear.
6. The result should be read at 5 minutes. Do not interpret the result after 10 minutes.



【DIRECTIONS FOR STRIP USE】
Allow the test, urine specimen, and/or controls to reach room temperature (15-30°C) prior to 
testing.
1. Bring the pouch to room temperature before opening it. Remove the test Strip from the sealed pouch and use it within one hour. 
2. With arrows pointing toward the urine specimen, immerse the test Strip vertically in the urine specimen for at least 10-15 seconds. Do not pass the maximum line (MAX) on the Test Strip when immersing the strip. See the illustration below. 
3. Place the test Strip on a non-absorbent flat surface, start the timer and wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10 minutes.


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